わが国の動物実験施設の微生物モニタリング成績*

* 結果は陽性施設数/ 検査施設数で表記

2011年度

マウス

陽性項目カテゴ
リー		製薬･他大学･研究所
Helicobacter bilis C 0 / 174   1 / 409 (0.2%)
Helicobacter hepaticus C 0 / 238   28 / 646 (4.3%)
Mycoplasma pulmonis B 2 / 433 (0.5%) 2 / 2,098 (0.1%)
Pasteurella pneumotropica D 0 / 288   116 / 1,861 (6.2%)
Pneumocystis murina (B) 1 / 72 (1.4%) 1 / 209 (0.5%)
Pseudomonas aeruginosa D 0 / 193   17 / 617 (2.8%)
Staphylococcus aureus D 10 / 93 (10.8%) 59 / 275 (21.5%)
Mouse hepatitis virus B 8 / 585 (1.4%) 24 / 2,215 (1.1%)
Murine norovirus C 5 / 22 (22.7%) 9 / 96 (9.4%)
Aspiculuris sp. C 0 / 282   60 / 1,841 (3.3%)
Syphacia sp. E 0 / 285   28 / 1,859 (1.5%)
Spironucleus sp. C 0 / 275   1 / 1,845 (0.1%)
Amoebas E 0 / 273   180 / 1,846 (9.8%)
Chilomastix sp. E 0 / 273   63 / 1,843 (3.4%)
Octomitus sp. E 0 / 273   147 / 1,845 (8.0%)
Trichomonad E 0 / 273   105 / 1,847 (5.7%)

 

ラット

陽性項目カテゴ
リー		製薬･他大学･研究所
CAR bacillus C 1 / 45 (2.2%) 0 / 24  
Clostridium piliforme
(Tyzzer菌)		 C 0 / 249   5 / 296 (1.7%)
Mycoplasma pulmonis B 0 / 243   3 / 279 (1.1%)
Pasteurella pneumotropica D 1 / 102 (1.0%) 7 / 161 (4.3%)
Pseudomonas aeruginosa D 0 / 32   3 / 51 (5.9%)
Staphylococcus aureus D 4 / 10 (40.0%) 13 / 19 (68.4%)
Aspiculuris sp. C 0 / 86   1 / 178 (0.6%)
Spironucleus sp. C 0 / 88   2 / 183 (1.1%)
Syphacia sp. E 0 / 91   17 / 183 (9.3%)
Amoebas E 0 / 86   18 / 177 (10.2%)
Chilomastix sp. E 0 / 86   2 / 177 (1.1%)
Octomitus sp. E 0 / 86   6 / 177 (3.4%)
Trichomonad E 0 / 86   8 / 177 (4.5%)

2010年度

マウス

陽性項目カテゴ
リー		製薬･企業大学･研究所
Helicobacter bilis C 0 / 41   1 / 318 (0.3%)
Helicobacter hepaticus C 2 / 68 (2.9%) 19 / 597 (3.2%)
Mycoplasma pulmonis B 0 / 196   2 / 1,700 (0.1%)
Pasteurella pneumotropica D 0 / 126   126 / 1,571 (8.0%)
Pneumocystis carinii
(P. murina)		 (B) 2 / 42 (4.8%) 2 / 109 (1.8%)
Pseudomonas aeruginosa D 0 / 49   22 / 421 (5.2%)
Staphylococcus aureus D 5 / 36 (13.9%) 41 / 142 (28.9%)
Mouse hepatitis virus B 0 / 227   39 / 1,852 (2.1%)
Murine norovirus C 0 / 5   8 / 68 (11.8%)
Sendai virus B 0 / 199   1 / 1,742 (0.1%)
Aspiculuris sp. C 0 / 95   59 / 1,463 (4.0%)
Syphacia sp. E 0 / 95   36 / 1,460 (2.5%)
Amoebas E 3 / 87 (3.5%) 160 / 1,493 (10.7%)
Chilomastix sp. E 0 / 83   68 / 1,489 (4.6%)
Octomitus sp. E 1 / 83 (1.2%) 142 / 1,489 (9.5%)
Trichomonad E 0 / 83   74 / 1,491 (5.0%)
外部寄生虫 C 0 / 83   1 / 1,458 (0.1%)

 

ラット

陽性項目カテゴ
リー		製薬･企業大学･研究所
Clostridium piliforme
(Tyzzer菌)		 C 2 / 146 (1.4%) 10 / 252 (4.0%)
Mycoplasma pulmonis B 0 / 132   2 / 356 (0.6%)
Pasteurella pneumotropica D 0 / 68   16 / 166 (9.6%)
Pseudomonas aeruginosa D 0 / 20   1 / 39 (2.6%)
Staphylococcus aureus D 5 / 8 (62.5%) 9 / 11 (81.8%)
Sialodacryoadenitis virus
(SDAV)		 C 0 / 145   1 / 246 (0.4%)
Aspiculuris sp. C 0 / 42   1 / 150 (0.7%)
Spironucleus sp. C 0 / 41   2 / 150 (1.3%)
Syphacia sp. E 0 / 43   20 / 150 (13.3%)
Amoebas E 0 / 41   7 / 150 (4.7%)
Chilomastix sp. E 0 / 41   2 / 150 (1.3%)
Octomitus sp. E 0 / 41   10 / 150 (6.7%)
Trichomonad E 0 / 41   12 / 150 (8.0%)

2009年度

マウス

陽性項目カテゴ
リー		製薬･企業大学･研究所
Helicobacter hepaticus C 2 / 98 (2.0%) 21 / 485 (4.3%)
Mycoplasma pulmonis B 0 / 259   5 / 1,527 (0.3%)
Pasteurella pneumotropica C 1 / 213 (0.5%) 75 / 1,544 (4.9%)
Pneumocystis carinii
(P. murina)		 (B) 0 / 26   4 / 57 (7.0%)
Pseudomonas aeruginosa D 0 / 108   17 / 396 (4.3%)
Staphylococcus aureus D 11 / 77 (14.3%) 36 / 124 (29.0%)
Mouse hepatitis virus B 0 / 284   21 / 1,621 (1.3%)
Sendai virus B 0 / 260   3 / 1,526 (0.2%)
Aspiculuris sp. C 0 / 191   43 / 1,402 (3.1%)
Syphacia sp. E 0 / 191   26 / 1,402 (1.9%)
消化管内原虫 C, E 5 / 188 (2.7%) 146 / 1,414 (10.3%)
外部寄生虫 C 0 / 188   0 / 1,414  

 

ラット

陽性項目カテゴ
リー		製薬･企業大学･研究所
CAR bacillus C 2 / 16   1 / 220 (0.5%)
Clostridium piliforme
(Tyzzer菌)		 C 1 / 176 (0.6%) 4 / 220 (1.8%)
Corynebacterium kutscheri C 0 / 115   2 / 185 (1.1%)
Mycoplasma pulmonis B 6 / 172 (3.5%) 6 / 220 (2.7%)
Pasteurella pneumotropica C 0 / 120   8 / 144 (5.6%)
Pseudomonas aeruginosa D 0 / 23   4 / 32 (12.5%)
Staphylococcus aureus D 5 / 13 (38.5%) 8 / 11 (72.7%)
Sialodacryoadenitis virus
(SDAV)		 C 0 / 193   2 / 216 (0.9%)
Syphacia sp. E 1 / 97 (1.0%) 11 / 162 (6.8%)
消化管内原虫 C, E 1 / 97 (1.0%) 10 / 162 (6.2%)

2007年度

マウス

陽性項目カテゴ
リー		製薬･企業大学･研究所
Helicobacter hepaticus C 0 / 74   32 / 498 (6.4%)
Mycoplasma pulmonis B 0 / 247   8 / 1,900 (0.4%)
Pasteurella pneumotropica D 0 / 135   114 / 1,564 (7.2%)
Pneumocystis carinii
(P. murina)		 (B) 0 / 8   1 / 87 (1.1%)
Pseudomonas aeruginosa D 0 / 31   11 / 466 (2.3%)
Staphylococcus aureus D 0 / 16   37 / 158 (23.4%)
Mouse hepatitis virus B 5 / 247 (2.0%) 49 / 1,564 (3.1%)
Sendai virus B 0 / 247   3 / 1,900 (0.2%)
Aspiculuris sp. C 0 / 129   31 / 1,660 (1.8%)
Syphacia sp. E 0 / 129   22 / 1,660 (1.3%)
消化管内原虫 C, E 2 / 129 (0.2%) 185 / 1,660 (11.1%)

 

ラット

陽性項目カテゴ
リー		製薬･企業大学･研究所
Clostridium piliforme
(Tyzzer菌)		 C 0 / 203   6 / 249 (2.4%)
Mycoplasma pulmonis B 0 / 203   9 / 249 (3.6%)
Pasteurella pneumotropica D 0 / 85   13 / 155 (8.3%)
Pseudomonas aeruginosa D 0 / 15   1 / 36 (2.7%)
Staphylococcus aureus D 4 / 7 (57.1%) 3 / 9 (33.3%)
Sendai virus B 1 / 203 (0.4%) 0 / 249  
Sialodacryoadenitis virus
(SDAV)		 C 0 / 203   2 / 249 (0.8%)
Syphacia overata E 0 / 76   17 / 143 (11.8%)
消化管内原虫 C, E 0 / 76   17 / 143 (11.8%)

2006年度

マウス

陽性項目カテゴ
リー		製薬･企業大学･研究所
Helicobacter hepaticus C 7 / 160 (4.4%) 21 / 466 (4.5%)
Helicobacter spp. C 4 / 23 (17.4%) 4 / 5 (80.0%)
Mycoplasma pulmonis B 4 / 673 (0.6%) 10 / 1,719 (0.6%)
Pasteurella pneumotropica D 4 / 319 (1.3%) 135 / 1,522 (8.9%)
Pneumocystis carinii
(P. murina)		 (B) 6 / 50 (12.0%) 2 / 82 (2.4%)
Pseudomonas aeruginosa D 10 / 76 (13.2%) 26 / 430 (6.0%)
Staphylococcus aureus D 13 / 39 (33.3%) 30 / 143 (20.1%)
Mouse hepatitis virus B 19 / 673 (2.8%) 47 / 1,719 (2.7%)
Sendai virus B 0 / 673   3 / 1,719 (0.2%)
Aspiculuris tetraptera C 0 / 216   37 / 1,333 (2.8%)
Syphacia overata E 0 / 216   30 / 1,333 (2.3%)
消化管内原虫 C, E 7 / 216 (3.2%) 206 / 1,333 (15.5%)
外部寄生虫 E 0 / 216   5 / 1,333 (0.4%)

 

ラット

陽性項目カテゴ
リー		製薬･企業大学･研究所
CAR bacillus C 2 / 29 (6.9%) 1 / 220 (0.4%)
Clostridium piliforme
(Tyzzer菌)		 C 1 / 384 (0.3%) 4 / 220 (1.8%)
Mycoplasma pulmonis B 6 / 384 (1.6%) 6 / 220 (2.7%)
Pasteurella pneumotropica D 9 / 140 (6.4%) 8 / 144 (5.6%)
Pseudomonas aeruginosa D 1 / 30 (3.3%) 4 / 32 (12.5%)
Staphylococcus aureus D 5 / 7 (71.4%) 8 / 11 (72.7%)
Sendai virus B 1 / 384 (0.3%) 0 / 220  
Sialodacryoadenitis virus
(SDAV)		 C 3 / 384 (0.3%) 0 / 220  
Aspiculuris tetraptera C 0 / 109   7 / 118 (5.9%)
Syphacia overata E 0 / 109   14 / 118 (11.9%)
消化管内原虫 C, E 0 / 109   12 / 118 (10.2%)